She hit out: "The reality is colleges' budgets are being slashed. It is no longer a question of if Mike Russell misled Parliament, the question is when. And isn't misleading Parliament the kind of offence which should cost a minister his job?"
The Labour leader continued her attack and said: "This week we found out that Mike Russell told a college chair he should resign because he no longer had any trust in him. No-one can have any trust in Mike Russell after this week.
"This week we found out Mike Russell told a college chair he would sack him if he had the power. But Mike Russell has misled this Parliament and the First Minister has the power to sack him." She demanded of the First Minister: "Why won't he sack a minister who is denying our young people an opportunity to go to college and, when challenged about, it misleads this Parliament?"
Mr Salmond insisted resource funding for colleges was £545 million in 2011-12 and £546 million in 2012-13. He hit out at Ms Lamont, saying he had been "rather expecting" her questions after Labour adviser Paul Sinclair had tweeted a call for Mr Russell to resign.
Ms Lamont hit back at Mr Salmond's response. "The idea that a juvenile trawl through the tweets of this world is any kind of response is a complete disgrace," she blasted. The Labour leader made the calls for the Education Secretary to be sacked at First Minster's Questions in the Scottish Parliament.